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STEMCELL Technologies Human Recombinant GM-CSF (CHO-expressed)
Descripción
- Granulocyte-macrophage colony-stimulating factor (GM-CSF) promotes the proliferation and differentiation of hematopoietic progenitor cells and the generation of neutrophils, eosinophils, and macrophages
- In synergy with other cytokines such as stem cell factor, IL-3, erythropoietin, and thrombopoietin, it also stimulates erythroid and megakaryocyte progenitor cells
- GM-CSF is produced by multiple cell types, including stromal cells, Paneth cells, macrophages, dendritic cells (DCs), endothelial cells, smooth muscle cells, fibroblasts, chondrocytes, and Th1 and Th17 T cells
- The receptor for GM-CSF (GM-CSFR) is composed of two subunits: the cytokine-specific α subunit (GMRα; CD116) and the common subunit βc (CD131) shared with IL-3 and IL-5 receptors
- GM-CSFR is expressed on hematopoietic cells, including progenitor cells and immune cells, as well as non-hematopoietic cells
Especificaciones
Especificaciones
| Nombre | CF, Colony-stimulating factor, CSF, CSF2, Granulocyte-macrophage colony-stimulating factor, Molgramostin, Sargramostim |
| Cantidad | 10 μg |
| Tipo de célula | Dendritic Cells; Hematopoietic Stem and Progenitor Cells; Mesoderm, PSC-Derived; Monocytes; Myeloid Cells |
| Grado de pureza o calidad | ≥95% |
Título del producto
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