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Gibco™ Human MANF Recombinant Protein, PeproTech®
Descripción
Recombinant Human MANF is an 18.1 kDa protein consisting of 158 amino acids, including 8 cysteine residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
The protein encoded by this gene is localized in the endoplasmic reticulum and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
Especificaciones
Especificaciones
| Número de acceso | P55145 |
| Para utilizar con (aplicación) | Functional Assay |
| Formulación | protein with no preservative |
| ID de gen (Entrez) | 7873 |
| Peso molecular | 18.1 kDa |
| Nombre | Human MANF |
| Cantidad | 100 μg |
| Fuente | E. coli |
| Estado normativo | RUO |
| Concentración de endotoxinas | <1 EU/ μg |
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Título del producto
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