missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Proteínas recombinantes
  4. Gibco™ Human LIF Recombinant Protein, PeproTech®

Gibco™ Human LIF Recombinant Protein, PeproTech®

Código de producto. 17860113
Change view
Click to view available options
Cantidad:
100 μg
1 mg
250 μg
25 μg
500 μg
50 μg
5 μg
Tamaño de la unidad:
1 miligramo
100 microgramos
25 microgramos
250 microgramos
5 microgramos
50 microgramos
500 microgramos
7 product options available for selection
Product selection table with 7 available options. Use arrow keys to navigate and Enter or Space to select.
Código de producto. Cantidad unitSize
17860113 100 μg 100 microgramos
17890413 1 mg 1 miligramo
17860383 250 μg 250 microgramos
17841843 25 μg 25 microgramos
17861843 500 μg 500 microgramos
17890003 50 μg 50 microgramos
17890033 5 μg 5 microgramos
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 7 options available.
7 options
Este artículo no se puede devolver. Vea la política de devoluciones
Código de producto. 17860113 Proveedor Gibco™ N.º de proveedor 30005100UG

Please to purchase this item. Need a web account? Register with us today!

Edge
Este artículo no se puede devolver. Vea la política de devoluciones

Descripción

Recombinant Protein

Recombinant Human LIF is a 19.7 kDa protein containing 180 amino acid residues, including three disulfide bonds. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Leukemia inhibitory factor (LIF) is a 20 kDa protein that belongs to the IL-6 receptor family. It binds to a heterodimeric membrane receptor made up of a LIF-specific subunit, gp190 or LIFR, and the subunit gp130, which is shared with the other members of the IL-6 family. LIF expression has been observed in various tissues including thymus, lung, and neuronal tissue. LIF can be up-regulated by pro-inflammatory cytokines such as TNFα and IL-17, and elevated levels of LIF have been found in cases of rheumatoid arthritis, neural injury, systemic inflammation, and tuberculosis. LIF displays diverse biological effects, but is best known for its ability to inhibit the differentiation of embryonic stem cells in mice and contribute to stem cell self-renewal.Human and mouse LIF share 79% sequence homology and exhibit cross-species activity. However, LIF inhibition of stem cell differentiation appears to be mouse-specific.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso P15018
Para utilizar con (aplicación) ELISA, Functional Assay, Western Blot
Formulación protein with no preservative
ID de gen (Entrez) 3976
Peso molecular 19.7 kDa
Nombre Human LIF
Cantidad 100 μg
Fuente E. coli
Estado normativo RUO
Concentración de endotoxinas <1 EU/ μg
Alias de gen CDF; cholinergic differentiation factor; cholinergic neuronal differentiation factor; d factor; DIA; differentiation inhibitory activity; differentiation-inducing factor; differentiation-stimulating factor; Emfilermin; hepatocyte-stimulating factor III; HILDA; human interleukin in DA cells; leukemia inhibitory factor; leukemia inhibitory factor (cholinergic differentiation factor); LIF; Melanoma-derived LPL inhibitor; MLPLI; myeloid leukaemia inhibitory factor
Nombre común LIF
Símbolo de gen Lif
Actividad biológica Determined by its ability to stimulate the proliferation of human TF-1 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^7 units/mg
Conjugado Unconjugated
Recombinante Recombinant
Secuencia SPLPITPVNA TCAIRHPCHN NLMNQIRSQL AQLNGSANAL FILYYTAQGE PFPNNLDKLC GPNVTDFPPF HANGTEKAKL VELYRIVVYL GTSLGNITRD QKILNPSALS LHSKLNATAD ILRGLLSNVL CRLCSKYHVG HVDVTYGPDT SGKDVFQKKK LGCQLLGKYK QIIAVLAQAF
Contenido y almacenamiento -20°C
Sistema de expresión E. coli
Formulario Lyophilized
Grado de pureza o calidad ≥ 98% by SDS-PAGE gel and HPLC analyses.
Mostrar más Mostrar menos
Título del producto
Seleccione un problema

Al hacer clic en Enviar, acepta que Fisher Scientific se ponga en contacto con usted en relación con los comentarios que ha proporcionado en este formulario. No compartiremos su información para ningún otro fin. Toda la información de contacto proporcionada se mantendrá de acuerdo con nuestra Política de Privacidad. Política de privacidad.