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Gibco™ Human IL-35 Recombinant Protein, PeproTech®
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Product Code. 17880163
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Cantidad:
10 x 50 μg
10 μg
2 x 50 μg
20 × 50 μg
2 μg
5 x 50 μg
50 μg
Unit Size:
1 miligramo
10 microgramos
100 microgramos
2 microgramos
250 microgramos
50 microgramos
500 microgramos
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Product Code. Cantidad unitSize
17880163 10 μg 10 microgramos
17881203 2 x 50 μg 100 microgramos
17821223 20 × 50 μg 1 miligramo
17831313 5 x 50 μg 250 microgramos
17870353 2 μg 2 microgramos
17850233 10 x 50 μg 500 microgramos
17820743 50 μg 50 microgramos
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This item is not returnable. View return policy
Product Code. 17880163 Supplier Gibco™ Supplier No. 2003710UG

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This item is not returnable. View return policy

Recombinant Protein

200-37-100UG will be provided as 2 x 50 μg (200-37-50UG). 200-37-1MG will be provided as 20 x 50 μg (200-37-50UG). 200-37-250UG will be provided as 5 x 50 μg (200-37-50UG). 200-37-500UG will be provided as 5 x 100 μg (200-37-50UG). Recombinant Recombinant Human IL-35 expressed in HEK293 cells contains 406 amino acid residues and has a calculated molecular weight of 45.8 kDa. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

IL-35, or Interleukin 35 is a cytokine belonging to the IL12 family, that is produced by regulatory T cells. It is a dimeric protein composed of IL-12-alpha and IL-27-beta chains. Members of this class of cytokines are important in influencing T helper cell differentiation and supressing inflammatory response. IL-35 is known to induce proliferation of regulatory T cells, and reduce the activity of helper Th17 cells.
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Specifications

Número de acceso P29459
Para utilizar con (aplicación) Control, Bioactivity
Formulación Protein with no preservative
ID de gen (Entrez) 3592
Peso molecular 45.8 kDa
Nombre Human IL-35
Método de purificación Purified
Cantidad 10 μg
Fuente HEK293 cells
Requisitos de almacenamiento -20°C
Estado normativo RUO
Concentración de endotoxinas <1 EU/μg
Alias de gen CLMF; CLMF p35; cytokine receptor; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; EBI3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; epstein-Barr virus-induced gene 3 protein; IL-12 subunit p35; IL-12, subunit p35; IL12A; IL-12A; IL12p35; IL27 subunit; IL-27 subunit beta; IL27B; IL-27B; il35; IL35 subunit; ILN; Interleukin; interleukin 12, p35; interleukin 12A; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); interleukin-12 alpha chain; interleukin-12 subunit alpha; Interleukin-27 subunit beta; Interleukin-35; NF cell stimulatory factor chain 1; NFSK; NK cell stimulatory factor chain 1; NKSF1; P35
Nombre común IL-35
Símbolo de gen IL12A
Actividad biológica Measured by its ability to inhibit proliferative activity of PBMCs.
Tipo de producto Protein
Conjugado Unconjugated
Recombinante Recombinant
Secuencia Alpha Subunit: RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY PCTSEEIDHE DITKDKTSTV EACLPLELTK NESCLNSRET SFITNGSCLA SRKTSFMMAL CLSSIYEDLK MYQVEFKTMN AKLLMDPKRQ IFLDQNMLAV IDELMQALNF NSETVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNAS Beta Subunit: RKGPPAALTL PRVQCRASRY PIAVDCSWTL PPAPNSTSPV SFIATYRLGM AARGHSWPCL QQTPTSTSCT ITDVQLFSMA PYVLNVTAVH PWGSSSSFVP FITEHIIKPD PPEGVRLSPL AERQLQVQWE PPGSWPFPEI FSLKYWIRYK RQGAARFHRV GPIEATSFIL RAVRPRARYY VQVAAQDLTD YGELSDWSLP ATATMSLGK
Contenido y almacenamiento -20°C
Actividad Measured by its ability to inhibit proliferative activity of PBMCs.
Sistema de expresión HEK293 cells
Formulario Lyophilized
Grado de pureza o calidad ≥ 90% by SDS-PAGE gel and HPLC analyses.
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