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Gibco™ Human IL-2 Recombinant Protein

Código de producto. 10642084
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Cantidad:
100 μg
10 μg
1 mg
40 μg
Tamaño de la unidad:
40 microgramos
cada uno
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Código de producto. 10642084

Marca: Gibco™ PHC0021

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Descrizione

Recombinant Protein

Carrier-Free Reconstitution: Centrifuge the vial briefly, before opening to bring the contents to the bottom. Reconstitute the lyophilized protein in100 mM acetic acid to 0.1-1.0 mg/mL to regain full activity. Make any further dilutions of the reconstituted protein in low endotoxin medium or buffered solution with FBS or tissue culture grade BSA. Storage: Store the lyophilized protein at 2-8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤-20°C (not in a frost-free freezer). Avoid repeated freeze-thaw cycles.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
TRUSTED_SUSTAINABILITY

Specifica

Número de acceso P60568
Para utilizar con (aplicación) Bioactivity
Formulación Protein with no preservative
ID de gen (Entrez) 3558
Peso molecular 15.5 kDa
Nombre Human IL-2
Método de purificación Purified
Cantidad 100 μg
Requisitos de almacenamiento 4°C
Estado normativo RUO
Concentración de endotoxinas <0.1 ng/μg
Alias de gen aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Nombre común IL-2
Símbolo de gen IL2
Actividad biológica ED50 < 0.5 ng/mL; determined by the dose-dependen proliferation of mouse CTLL-2 cells.
Tipo de producto Protein
Conjugado Unconjugated
Especie Human
Recombinante Recombinant
Contenido y almacenamiento 4°C
Clasificación Carrier-Free
Actividad ED50 < 0.5 ng/mL; determined by the dose-dependen proliferation of mouse CTLL-2 cells.
Nivel de endotoxinas <0.1 ng/μg
Condiciones de envío Wet Ice
Sistema de expresión E. coli
Familia de proteínas Cytokines & Receptors
Forma de proteína Recombinant, Ligand, Mutant
Formulario Lyophilized
Subtipo de proteína Interleukins
Categoría de investigación Immunology, Signal Transduction, Stem Cell Research, Angiogenesis, Oncology
Línea de productos Gibco
Grado de pureza o calidad >95% by SDS-PAGE
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