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Invitrogen™ Human CACNA1I (aa 1842-1934) Control Fragment Recombinant Protein

Código de producto. 30212326
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
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30212326 100 μL 100 microlitros
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Código de producto. 30212326 Proveedor Invitrogen™ N.º de proveedor RP110066

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Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (78%), Rat (78%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-144944 (PA5-144944. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

CaV3.3 encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by CaV3.3 is characterized by a slower activation and inactivation compared to other T-type calcium channels. CaV3.3 may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants of CaV3.3. Voltage-gated calcium channels (CaV) are present in the membrane of most excitable cells and mediate calcium influx in response to depolarization, an proteins such as CaV3.3 regulate intracellular processes such as contraction, secretion, neurotransmission and gene expression. Diseases associated with CACNA1I include Childhood Absence Epilepsy.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso Q9P0X4
Concentración ≥5.0 mg/mL
Para utilizar con (aplicación) Blocking Assay, Control
Formulación 1 M urea, PBS with no preservative; pH 7.4
ID de gen (Entrez) 8911
Nombre Human CACNA1I (aa 1842-1934) Control Fragment
Cantidad 100 μL
Estado normativo RUO
Alias de gen Ca(v)3.3; CACNA1I; calcium channel, voltage-dependent, alpha 1 I subunit; calcium channel, voltage-dependent, T type, alpha 1 I subunit; calcium voltage-gated channel subunit alpha1 I; Cav3.3; CaVT0.3; hypothetical gene supported by NM_020084; KIAA1120; low voltage-activated T-type calcium channel alpha-1 subunit (CACNA1I); low-voltage-activated calcium channel alpha13.3; RP1-172B20.4; voltage-dependent calcium channel; voltage-dependent T-type calcium channel subunit alpha-1 I; Voltage-gated calcium channel subunit alpha Cav3.3
Nombre común CACNA1I
Símbolo de gen CACNA1I
Conjugado Unconjugated
Especie Human
Recombinante Recombinant
Etiqueta de proteína His-ABP-tag
Secuencia HHDKQEVQLAETEAFSLNSDRSSSILLGDDLSLEDPTACPPGRKDSKGELDPPEPMRVGDLGECFFPLSSTAVSPDPENFLCEMEEIPFNPVR
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Sistema de expresión E. coli
Formulario Liquid
Grado de pureza o calidad >80% by SDS-PAGE and Coomassie blue staining
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