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Gibco™ Human BMP-4 Recombinant Protein

Código de producto. 11310852
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Cantidad:
100 μg
10 μg
1 mg
Tamaño de la unidad:
cada uno
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Código de producto. 11310852 Proveedor Gibco™ N.º de proveedor PHC9531

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Descripción

Recombinant Protein

Carrier-Free Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute lyophilized recombinant human BMP-4 in 4 mM HCl containing 0.1% human serum albumin. Further dilutions should be made in low endotoxin medium or a buffered solution containing a carrier protein such as heat inactivated FCS or tissue culture grade BSA. Storage: Store this lyophilized preparation at =-20°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at =-20°C. Avoid repeated freeze/thaw cycles.

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso P12644, P21275
Para utilizar con (aplicación) Bioactivity
Formulación HCl with no preservative
ID de gen (Entrez) 12159, 652
Peso molecular 34 kDa
Nombre Human BMP-4
Método de purificación Purified
Cantidad 100 μg
Requisitos de almacenamiento -20°C
Estado normativo RUO
Concentración de endotoxinas <1 EU/μg
Alias de gen BMP; BMP2B; BMP-2B; Bmp2b1; Bmp2b-1; Bmp4; Bmp-4; BOMPR4A; Bone morphogenetic protein; Bone morphogenetic protein 2B; bone morphogenetic protein 4; bone morphogenetic protein 4 preproprotein; DVR4; Dvr-4; MCOPS6; OFC11; ZYME
Nombre común BMP4
Símbolo de gen BMP4
Actividad biológica ED50 = 2 - 10 ng/mL; determined by the dose-dependent induction of alkaline phosphatase production in ATDC-5 cells.
Tipo de producto Protein
Conjugado Unconjugated
Especie Human
Recombinante Recombinant
Contenido y almacenamiento -20°C
Clasificación Carrier-Free
Actividad ED50 = 2 - 10 ng/mL; determined by the dose-dependent induction of alkaline phosphatase production in ATDC-5 cells.
Bioensayo Induction of alkaline phosphatase in ATDC5 cells
Nivel de endotoxinas <1 EU/ml
Condiciones de envío Dry Ice
Sistema de expresión HEK293 cells
Familia de proteínas Growth Factors & Receptors
Forma de proteína Recombinant, Ligand
Formulario Lyophilized
Subtipo de proteína BMPs (Bone Morphogenetic Proteins) & Related Factors
Categoría de investigación Bone Research, Stem Cell Research, Differentiation
Línea de productos Gibco
Grado de pureza o calidad >95% by SDS-PAGE
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