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  8. GSK1904529A, MedChemExpress

GSK1904529A, MedChemExpress

Código de producto. 16480377
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Código de producto. 16480377 Proveedor Medchem Express N.º de proveedor HY10524

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Description

MedChemExpress GSK1904529A is a potent, selective, orally active, and ATP-competitive inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR), with IC50s of 27 and 25 nM, respectively. GSK1904529A shows poor activity (IC50>1 μM) in 45 other serine/threonine and tyrosine kinases. GSK1904529A exhibits anti-tumor activity.

GSK1904529A is a potent, selective, orally active, and ATP-competitive inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR), with IC50s of 27 and 25 nM, respectively. GSK1904529A shows poor activity (IC50>1 μM) in 45 other serine/threonine and tyrosine kinases. GSK1904529A exhibits anti-tumor activity.

Specifications

Nombre del producto químico o material GSK1904529A
CAS 1089283-49-7
Color Yellow
Notas de grado de pureza Research
Fórmula molecular C44H47F2N9O5S
Cantidad 50 mg
Información de solubilidad DMSO : 50 mg/mL (58.69 mM; Need ultrasonic)
SMILES O=C(C1=CC(C2=C(N3C=CC=CC3=N2)C4=NC(NC5=CC(CC)=C(C=C5OC)N6CCC(CC6)N7CCN(CC7)S(=O)(C)=O)=NC=C4)=CC=C1OC)NC8=C(C=CC=C8F)F
Peso molecular (g/mol) 851.96
Formula Weight (peso de la fórmula) 851.96
Porcentaje de pureza 99.66%
Grado Research
Forma física Solid
Para utilizar con (aplicación) Cancer-Kinase/protease
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Research purposes only

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