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Invitrogen™ Human GM-CSF Recombinant Protein
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Cantidad:
20 μg
Tamaño de la unidad:
20 microgramos
Descripción
This product cross-reacts with bacteria, Mouse, Leech, Porcine, and Chicken GM-CSF. For dilution, use a buffer containing carrier protein, e.g. PBS with 1% BSA or a neutral media containing 10% FCS and freeze in aliquots at -70°C. Sterile-filtered through a 0.2 micron filter. Reconstitute with 0.5 mL of distilled water.
The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.

Especificaciones
Especificaciones
Número de acceso | P04141 |
Para utilizar con (aplicación) | ELISA, Immunoprecipitation, Western Blot |
Formulación | protein with no preservative |
ID de gen (Entrez) | 1437 |
Peso molecular | 14.6 kDa |
Nombre | Human GM-CSF |
Cantidad | 20 μg |
Fuente | E. Coli |
Estado normativo | RUO |
Alias de gen | colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim |
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