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Invitrogen™ Human FRAP1 (mTOR), GST Tag Recombinant Protein

Recombinant Protein

Marca:  Invitrogen™ PV4753

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Código de producto. 10012913

  • 1280.00€ / cada uno

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Descripción

Descripción

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Catalytic Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic System Compatibility: LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™

FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene results in Smith-Kingsmore syndrome.
TRUSTED_SUSTAINABILITY
Especificaciones

Especificaciones

P42345
Kinase Assay
2475
Human FRAP1 (mTOR), GST Tag
2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS
PIKK Kinase Family
Unconjugated
Recombinant
-80°C, Avoid Freeze/Thaw Cycles
Ser⁄Thr Kinases: Atypical
LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™
FK506 binding protein 12-rapamycin associated protein 1
Kinases & Inhibitors
Liquid
Signal Transduction, Drug Development, Oncology
See Label
50 mM tris with 0.1% polysorbate 20, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
163.9 kDa
10 μg
mTOR
1360-2549
Human
GST-tag
Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Dry Ice
mTOR, FRAP1
Insect cells
Recombinant, Catalytic
Serine/Threonine Kinases
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