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Invitrogen™ Claudin 5 Monoclonal Antibody (4C3C2), Alexa Fluor™ 488
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Código de producto. 10237304
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Cantidad:
100 μg
Tamaño de la unidad:
cada uno
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10237304 100 μg cada uno
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Código de producto. 10237304 Proveedor Invitrogen™ N.º de proveedor 352588

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522.50 EUR hasta el 2026-06-30
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Descripción

Mouse Monoclonal Antibody

Reactivity has been confirmed with rat, human and mouse Claudin-5 using rat lung, mouse kidney, mouse small intestine, mouse lung homogenates, human colon tissue, and CACO-2 human cell line. This antibody reacts specifically with the ~ 22-24 kDa endogenous Claudin-5 protein. Excitation/Peak Emission (nm): 495/519.

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno Claudin 5
Aplicaciones ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
Clasificación Monoclonal
Clon 4C3C2
Concentración 0.5 mg/mL
Conjugado Alexa Fluor 488
Formulación PBS with 4mg/mL BSA and 0.1% sodium azide; pH 7.4
génica CLDN5
N.º de referencia del gen O00501, O54942, Q9JKD6
Alias de gen AI854493; AWAL; BEC1; Brain endothelial cell clone 1 protein; claudin 5; claudin 5 (transmembrane protein deleted in velocardiofacial syndrome); claudin-5; claudin-5 protein; Cldn5; CPETRL1; lung-specific membrane protein; MBEC1; TMDVCF; TMVCF; Transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome; Unknown (protein for MGC:138054)
Símbolos de los genes CLDN5
Especie del huésped Mouse
Inmunógeno Synthetic peptide derived from the mouse Claudin-5 protein.
Método de purificación Protein A
Cantidad 100 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 12741, 65131, 7122
Especies diana Human, Mouse, Rat
Contenido y almacenamiento 4°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG1
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