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Invitrogen™ Human CDK9/Cyclin K, His Tag Recombinant Protein

Código de producto. 11593647
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Cantidad:
10 μg
Tamaño de la unidad:
10 microgramos
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Código de producto. Cantidad unitSize
11593647 10 μg 10 microgramos
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Código de producto. 11593647 Proveedor Invitrogen™ N.º de proveedor PV4335

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Descripción

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length

CDK9 is a serine/threonine kinase which when complexed with CyclinT1 forms an active holoenzyme complex. This complex plays a key role in regulating the eukaryotic cell cycle. CDK9 is coexpressed and copurified with CyclinT1. CDK9 regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors. CDK9 promotes RNA synthesis in genetic programs for cell growth, differentiation, and viral pathogenesis. The CDK9/cyclin-K complex also has kinase activity towards CTD of RNAPII and can substitute for CDK9/cyclin-T P-TEFb in vitro. Chronic activation of CDK9 causes cardiac myocyte enlargement leading to cardiac hypertrophy and confers a predisposition to heart failure.
TRUSTED_SUSTAINABILITY

Especificaciones

Número de acceso P50750
Concentración See Label
Para utilizar con (aplicación) Kinase Assay
Formulación 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
ID de gen (Entrez) 1025
Peso molecular 91.8 kDa
Nombre Human CDK9/Cyclin K, His Tag
Cantidad 10 μg
Estado normativo For research use only. Not for use in diagnostic procedures
Alias de gen C-2 k; CDC2L4; CDC2-related kinase; Cdk9; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; CTK1; cyclin dependent kinase 9; cyclin-dependent kinase 9; cyclin-dependent kinase 9 (CDC2-related kinase); PITALRE; RP11-228B15.5; serine/threonine protein kinase PITALRE; Serine/threonine-protein kinase PITALRE; TAK; Tat-associated kinase complex catalytic subunit
Nombre común CDK9
Familia Quinasa CDK and CHK
Tipo de producto CDK9/Cyclin K Recombinant Human Protein
Conjugado Unconjugated
Especie Human
Recombinante Recombinant
Etiqueta de proteína His-tag
Secuencia Full length
Contenido y almacenamiento -80°C, Avoid Freeze/Thaw Cycles
Sistema de expresión Baculovirus
Familia de proteínas Kinase and inhibitors
Formulario Liquid
Subtipo de proteína Serine/threonine kinase
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