missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Productos químicos
  4. Compuestos orgánicos
  5. Bencenoides
  6. Benceno y derivados sustituidos
  7. Fluorobencenos
  8. Avapritinib, MedChemExpress

Avapritinib, MedChemExpress

Código de producto. 16494636
Encompass_Preferred
Cambiar vista
Click to view available options
Cantidad:
1 mg
5 mg
10 mg
25 mg
50 mg
100 mg
Tamaño de la unidad:
1 miligramo
10 miligramos
100 miligramos
25 miligramos
5 miligramos
50 miligramos
6 product options available for selection
Product selection table with 6 available options. Use arrow keys to navigate and Enter or Space to select.
Código de producto. Cantidad unitSize
16494636 100 mg 100 miligramos
16486137 5 mg 5 miligramos
16479936 50 mg 50 miligramos
16423418 10 mg 10 miligramos
16422766 25 mg 25 miligramos
16410779 1 mg 1 miligramo
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 6 options available.
6 options
Este artículo no se puede devolver. Vea la política de devoluciones
Código de producto. 16494636 Proveedor Medchem Express N.º de proveedor HY101561

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress Avapritinib (BLU-285) is a highly potent, selective, and orally active KIT and PDGFRA activation loop mutant kinases inhibitor with IC50s of 0.27 and 0.24 nM for KIT D816V and PDGFRA D842V, respectively. Avapritinib (BLU-285) binds the active conformation of the kinase and shows antitumor activity. Avapritinib (BLU-285) attenuates the transport function of both ABCB1 and ABCG2.

Avapritinib (BLU-285) is a highly potent, selective, and orally active KIT and PDGFRA activation loop mutant kinases inhibitor with IC50s of 0.27 and 0.24 nM for KIT D816V and PDGFRA D842V, respectively. Avapritinib (BLU-285) binds the active conformation of the kinase and shows antitumor activity. Avapritinib (BLU-285) attenuates the transport function of both ABCB1 and ABCG2.

Specifications

Nombre del producto químico o material Avapritinib
CAS 1703793-34-3
Color Off-White
Notas de grado de pureza Research
Fórmula molecular C26H27FN10
Cantidad 100 mg
Sinónimo BLU-285
Información de solubilidad DMSO : ≥ 83.33 mg/mL (167.14 mM)
SMILES CN1N=CC(C2=CN3C(C(N4CCN(C5=NC=C([C@@](C)(N)C6=CC=C(F)C=C6)C=N5)CC4)=NC=N3)=C2)=C1
Peso molecular (g/mol) 498.56
Formula Weight (peso de la fórmula) 498.56
Porcentaje de pureza 99.46%
Grado Research
Forma física Solid
Para utilizar con (aplicación) Cancer-Kinase/protease
Show More Show Less

Research purposes only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.