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  8. ABBV-744, MedChemExpress

ABBV-744, MedChemExpress

Código de producto. 16467277
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Cantidad:
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Tamaño de la unidad:
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25 miligramos
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Código de producto. Cantidad unitSize
16467277 5 mg 5 miligramos
16450867 50 mg 50 miligramos
16424568 10 mg 10 miligramos
16403136 25 mg 25 miligramos
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Product Code. 16467277 Supplier Medchem Express Supplier No. HY112090

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Description

MedChemExpress ABBV-744 is a first-in-class, orally active and selective inhibitor of the BDII domain of BET family proteins with IC50 values ranging from 4 to 18 nM for BRD2, BRD3, BRD4 and BRDT. ABBV-744 is primarily metabolized by CYP3A4 with drug-like properties enable the investigation of its antitumor efficacy and tolerability.

ABBV-744 is a first-in-class, orally active and selective inhibitor of the BDII domain of BET family proteins with IC50 values ranging from 4 to 18 nM for BRD2, BRD3, BRD4 and BRDT. ABBV-744 is primarily metabolized by CYP3A4 with drug-like properties enable the investigation of its antitumor efficacy and tolerability.

Specifications

Nombre del producto químico o material ABBV-744
CAS 2138861-99-9
Color Blanco
Notas de grado de pureza Research
Fórmula molecular C28H30FN3O4
Cantidad 5 mg
Información de solubilidad DMSO : 100 mg/mL (203.44 mM; Need ultrasonic)
SMILES CC(O)(C)C1=CC(C(C2=C3NC(C(NCC)=O)=C2)=CN(C)C3=O)=C(OC4=C(C)C=C(F)C=C4C)C=C1
Peso molecular (g/mol) 491.55
Formula Weight (peso de la fórmula) 491.55
Porcentaje de pureza 98.22%
Grado Research
Forma física Powder
Para utilizar con (aplicación) Cancer-programmed cell death
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Research purposes only

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