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CAS RN 159351-69-6

H3CO(R)(S)(R)OOH(R)CH3(S)O(R)H3CCH3(R)OH(R)OH3CO(R)CH3(S)CH3CH3(S)(S)(R)H3C(R)HOOOON(S)OOOH3C(Z)(Z)(Z)(Z)

CAS RN 159351-69-6

IUPAC Nombre: (1R,9S,12S,15R,16Z,18R,19R,21R,23S,24E,26Z,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Sinónimos: everolimus sdz rad RAD everolimus (substance) certican sdz-rad everolimus (product)
Peso molecular (g/mol): 958.24
Fórmula molecular: C53H83NO14
InChi Key: HKVAMNSJSFKALM-CNPAPGRKSA-N
SMILES: CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)/[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C/C=C(C)/[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1OCCO
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1 – 6 de 6 resultados
1

Everolimus, Thermo Scientific™

CAS: 159351-69-6 Fórmula molecular: C53H83NO14 Peso molecular (g/mol): 958.24 Número MDL: MFCD07785165 Clave InChI: HKVAMNSJSFKALM-PWMUVMERSA-N PubChem CID: 129317877 SMILES: CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OCCO)C)C)O)OC)C)C)C)OC

Clave InChI HKVAMNSJSFKALM-PWMUVMERSA-N
PubChem CID 129317877
Fórmula molecular C53H83NO14
CAS 159351-69-6
Peso molecular (g/mol) 958.24
Número MDL MFCD07785165
SMILES CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OCCO)C)C)O)OC)C)C)C)OC
2
Promociones disponibles

Tocris Bioscience™ Everolimus
GREENER_CHOICE

mTOR inhibitor;immunosuppressant

3

Everolimus, TRC

CAS: 159351-69-6 Fórmula molecular: C53 H83 N O14 Peso molecular (g/mol): 958.22 Sinónimo: Rapamycin, 42-O-(2-hydroxyethyl)-,23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, rapamycin deriv.,42-O-(2-Hydroxyethyl)rapamycin,40-O-(2-Hydroxyethyl)rapamycin,Afinitor,Afinitor Disperz,Certican,Everolimus,RAD,RAD 001,SDZ-RAD,XIENCE V,Xience,Zortress SMILES: C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OCCO)C)/C)O)OC)C)C)/C)OC

Sinónimo Rapamycin, 42-O-(2-hydroxyethyl)-,23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, rapamycin deriv.,42-O-(2-Hydroxyethyl)rapamycin,40-O-(2-Hydroxyethyl)rapamycin,Afinitor,Afinitor Disperz,Certican,Everolimus,RAD,RAD 001,SDZ-RAD,XIENCE V,Xience,Zortress
Fórmula molecular C53 H83 N O14
CAS 159351-69-6
Peso molecular (g/mol) 958.22
SMILES C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OCCO)C)/C)O)OC)C)C)/C)OC
4

STEMCELL Technologies Everolimus

mTOR pathway inhibitor; Inhibits FKBP-12

ENCOMPASS_PREFERRED
Sinónimo RAD001; SDZ-RAD; Xience
Fórmula molecular C53H83NO14
CAS 159351-69-6
Pureza ≥95%
5

Everolimus, MedChemExpress

MedChemExpress Everolimus (RAD001) is a Rapamycin (HY-10219) derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities.

ENCOMPASS_PREFERRED
Sinónimo RAD001 SDZ-RAD
Información de solubilidad DMSO : ≥ 54 mg/mL (56.35 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Forma física Powder
Almacenamiento recomendado Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Peligro para la salud 1 H351∣H361
Color Blanco
SMILES O=C([C@@]1(O)[C@@H](CC[C@@H](C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@@H](C)C([C@@H]([C@@H](/C(C)=C/[C@H]2C)O)OC)=O)C)OC)O1)C)C(N3CCCC[C@H]3C(O[C@@H](CC2=O)[C@@H](C[C@H]4C[C@H]([C@H](OCCO)CC4)OC)C)=O)=O
Notas de grado de pureza Research
Duración de almacenamiento Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formula Weight (peso de la fórmula) 958.22
Fórmula molecular C53H83NO14
CAS 159351-69-6
Nombre del producto químico o material Everolimus
Porcentaje de pureza 98.0%
Peso molecular (g/mol) 958.22
Grado Research
Para utilizar con (aplicación) Cancer-Kinase/protease
6

Tocris Bioscience™ Everolimus
GREENER_CHOICE

mTOR inhibitor;immunosuppressant

ENCOMPASS