CAS RN 877636-42-5
IUPAC Nombre:
4-oxo-6-[(pyrimidin-2-ylsulfanyl)methyl]-4H-pyran-3-yl 4-nitrobenzoate
Sinónimos:
4-oxo-6-[(pyrimidin-2-ylsulfanyl)methyl]pyran-3-yl 4-nitrobenzoate
Peso molecular (g/mol):
385.35
Fórmula molecular:
C17H11N3O6S
InChi Key:
UASIRTUMPRQVFY-UHFFFAOYSA-N
SMILES:
[O-][N+](=O)C1=CC=C(C=C1)C(=O)OC1=COC(CSC2=NC=CC=N2)=CC1=O
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1
Tocris Bioscience™ ML 221
CAS: 877636-42-5 Fórmula molecular: C17H11N3O6S
2
ML221, MedChemExpress
MedChemExpress ML221 is a potent apelin (APJ) functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays.
