CAS RN 5852-78-8
IUPAC Nombre:
8-hydroxyquinoline-5-carboxylic acid
Sinónimos:
8-hydroxyquinoline-5-carboxylic acid
Peso molecular (g/mol):
189.17
Fórmula molecular:
C10H7NO3
InChi Key:
JGRPKOGHYBAVMW-UHFFFAOYSA-N
SMILES:
OC(=O)C1=CC=C(O)C2=NC=CC=C12
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1
Tocris Bioscience™ IOX 1
CAS: 5852-78-8 Fórmula molecular: C10H7NO3
2
IOX1, MedChemExpress
MedChemExpress IOX1, 5-Carboxy-8-hydroxyquinoline, is a potent broad‐spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 inhibits KDM4C, KDM4E, KDM2A, KDM3A and KDM6B with IC50 values of 0.6 μM, 2.3 μM, 1.8 μM, 0.1 μM and 1.4 μM, respectively. IOX1 also inhibits ALKBH5.
