CAS RN 500-64-1
Kawain, TRC
CAS: 500-64-1 Fórmula molecular: C14 H14 O3 Peso molecular (g/mol): 230.26 Sinónimo: [R-(E)]-5,6-Dihydro-4-methoxy-6-(2-phenylethenyl)-2H-pyran-2-one,(R)-5,6-Dihydro-4-methoxy-6-styryl-2H-pyran-2-one,(+)-Kavain,(+)-Kawain,(R)-(+)-Kavain,Gonosan,Kavain,Kawain,NSC 112162,d-Kawain Nombre IUPAC: (2R)-4-metoxi-2-[(E)-2-feniletenilo]-2,3-dihidropiran-6-uno SMILES: COC1=CC(=O)O[C@H](C1)\C=C\c2ccccc2
(+)-Kavain, MedChemExpress
MedChemExpress (+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels. (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied.