CAS RN 391210-10-9
IUPAC Nombre:
N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
Sinónimos:
N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
Peso molecular (g/mol):
482.2
Fórmula molecular:
C16H14F3IN2O4
InChi Key:
SUDAHWBOROXANE-UHFFFAOYNA-N
SMILES:
OCC(O)CONC(=O)C1=C(NC2=C(F)C=C(I)C=C2)C(F)=C(F)C=C1
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Promociones disponibles
Tocris Bioscience™ PD 0325901
Tocris Bioscience™ PD 0325901
CAS: 391210-10-9 Fórmula molecular: C16H14F3IN2O4
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Mirdametinib, MedChemExpress
MedChemExpress Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a Kiapp of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts.
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