CAS RN 304896-28-4

IUPAC Nombre: 2-cyano-3-[5-(2,5-dichlorophenyl)furan-2-yl]-N-(quinolin-5-yl)prop-2-enamide

Sinónimos: 2-cyano-3-[5-(2,5-dichlorophenyl)furan-2-yl]-N-(quinolin-5-yl)prop-2-enamide

Peso molecular (g/mol): 434.28

Fórmula molecular: C23H13Cl2N3O2

InChi Key: SVENPFFEMUOOGK-UHFFFAOYSA-N

SMILES: ClC1=CC(C2=CC=C(O2)C=C(C#N)C(=O)NC2=C3C=CC=NC3=CC=C2)=C(Cl)C=C1

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MedChemExpress AGK2 is a selective SIRT2 inhibitor with an IC50 of 3.5 μM. AGK2 inhibits SIRT1 and SIRT3 with IC50s of 30 and 91 μM, respectively.

Información de solubilidad	DMSO : 12.5 mg/mL (28.78 mM; Need ultrasonic)
Forma física	Solid
Almacenamiento recomendado	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Color	Green Yellow
SMILES	O=C(NC1=C2C=CC=NC2=CC=C1)/C(C#N)=C/C3=CC=C(C4=CC(Cl)=CC=C4Cl)O3
Notas de grado de pureza	Research
Duración de almacenamiento	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formula Weight (peso de la fórmula)	434.27
Fórmula molecular	C₂₃H₁₃Cl₂N₃O₂
CAS	304896-28-4
Nombre del producto químico o material	AGK2
Porcentaje de pureza	97.0%
Peso molecular (g/mol)	434.27
Grado	Research
Para utilizar con (aplicación)	Cancer-programmed cell death