CAS RN 289483-69-8
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Tocris Bioscience™ E 7820
α2 integrin inhibitor; anti-angiogenic
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E7820, MedChemExpress
MedChemExpress E7820 (ER68203-00), an orally active aromatic sulfonamide derivative, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium. E7820 inhibits rat aorta angiogenesis with an IC50 of 0.11 μg/ml. E7820 modulates α-1, α-2, α-3, and α-5 integrin mRNA expression. Antiangiogenic and antitumor activity.
