CAS RN 204067-01-6
IUPAC Nombre:
3-(1H-indol-3-yl)-N-{[1-(5-methoxypyridin-2-yl)cyclohexyl]methyl}-2-methyl-2-{[(4-nitrophenyl)carbamoyl]amino}propanamide
Sinónimos:
3-(1H-indol-3-yl)-N-{[1-(5-methoxypyridin-2-yl)cyclohexyl]methyl}-2-methyl-2-{[(4-nitrophenyl)carbamoyl]amino}propanamide
Peso molecular (g/mol):
584.68
Fórmula molecular:
C32H36N6O5
InChi Key:
NNFUWNLENRUDHR-UHFFFAOYNA-N
SMILES:
COC1=CN=C(C=C1)C1(CNC(=O)C(C)(CC2=CNC3=CC=CC=C23)NC(=O)NC2=CC=C(C=C2)[N+]([O-])=O)CCCCC1
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PD176252, MedChemExpress
MedChemExpress PD176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively; PD176252 is also an agonist of N-Formyl peptide receptor1/2 (FPR1/FPR2), with EC50s of 0.31 and 0.66 μM in HL-60 cells.
