CAS RN 198481-32-2
Bazedoxifeno, TRC
CAS: 198481-32-2 Fórmula molecular: C30 H34 N2 O3 Peso molecular (g/mol): 470.6 Sinónimo: 1H-Indol-5-ol, 1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-,1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol,Bazedoxifene,WAY 140424 Nombre IUPAC: 1-[[4-[2-(azepano-1-il)etoxi]fenil]metil]-2-(4-hidroxifenil)-3-metilindol-5-ol SMILES: OC=1C=CC(=CC1)C2=C(C3=CC(O)=CC=C3N2CC4=CC=C(OCCN5CCCCCC5)C=C4)C
Bazedoxifene, MedChemExpress
MedChemExpress Bazedoxifene (TSE-424) is an oral, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene can be used for the research of osteoporosis. Bazedoxifene also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer.