CAS RN 1982372-88-2
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Tocris Bioscience™ A 196
Potent and selective SUV420H1/H2 inhibitor
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A-196, MedChemExpress
MedChemExpress A-196 is a potent and selective inhibitor of SUV420H1 and SUV420H2 with IC50 values of 25 nM and 144 nM, respectively. A-196 inhibits SUV4-20 biochemically in a substrate-competitive manner. A-196 represents a first-in-class chemical probe of SUV4-20 to investigate the role of histone methyltransferases in genomic integrity.
