CAS RN 1622849-58-4

IUPAC Nombre: 5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl)-1,2-oxazole-3-carboxamide

Sinónimos: 5-benzyl-N-(5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl)-1,2-oxazole-3-carboxamide

Peso molecular (g/mol): 377.4

Fórmula molecular: C21H19N3O4

InChi Key: KNOUWGGQMADIBV-UHFFFAOYNA-N

SMILES: CN1C2=CC=CC=C2OCC(NC(=O)C2=NOC(CC3=CC=CC=C3)=C2)C1=O

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Thermo Scientific™ GSK481, 95 %

Precio y disponibilidad

GSK481, MedChemExpress

MedChemExpress GSK481 is a highly potent, selective, and specific receptor interacting protein 1 (RIP1) kinase inhibitor with an IC50 of 1.3 nM, which inhibits Ser166 phosphorylation in wild-type human RIP1 (IC50=2.8 nM). GSK481 also exhibits excellent translation in the U937 cellular assay with an IC50 of 10 nM.

Precio y disponibilidad
Especificaciones

Información de solubilidad	DMSO : ≥ 35 mg/mL (92.74 mM)
Forma física	Solid
Almacenamiento recomendado	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Color	Marrón
SMILES	O=C(C1=NOC(CC2=CC=CC=C2)=C1)N[C@H]3COC4=CC=CC=C4N(C)C3=O
Notas de grado de pureza	Research
Duración de almacenamiento	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Formula Weight (peso de la fórmula)	377.39
Fórmula molecular	C₂₁H₁₉N₃O₄
CAS	1622849-58-4
Nombre del producto químico o material	GSK481
Porcentaje de pureza	98.0%
Peso molecular (g/mol)	377.39
Grado	Research
Para utilizar con (aplicación)	COVID-19-immunoregulation

CAS RN 1622849-58-4

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