CAS RN 118414-82-7
IUPAC Nombre:
3-[3-(butylsulfanyl)-1-[(4-chlorophenyl)methyl]-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid
Sinónimos:
3-[3-(butylsulfanyl)-1-[(4-chlorophenyl)methyl]-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid
Peso molecular (g/mol):
472.08
Fórmula molecular:
C27H34ClNO2S
InChi Key:
VFMGWQLOCZBFCK-UHFFFAOYSA-N
SMILES:
CCCCSC1=C(CC(C)(C)C(O)=O)N(CC2=CC=C(Cl)C=C2)C2=CC=C(C=C12)C(C)C
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3
resultados
1
Tocris Bioscience™ MK 886
Inhibitor of 5-lipoxygenase-activating protein (FLAP)
2
MK-886, TRC
CAS: 118414-82-7 Fórmula molecular: C27H34ClNO2S Peso molecular (g/mol): 472.08 Sinónimo: MK-886,L 663536 SMILES: CC(C)c1ccc2c(c1)c(SC(C)(C)C)c(CC(C)(C)C(=O)O)n2Cc3ccc(Cl)cc3
3
MK-886, MedChemExpress
MedChemExpress MK-886 (L 663536) is a potent, cell-permeable and orally active FLAP (IC50 of 30 nM) and leukotriene biosynthesis (IC50s of 3 nM and 1.1 μM in intact leukocytes and human whole blood, respectively) inhibitor. MK-886 is also a non-competitive PPARα antagonist and can induce apoptosis.
