CAS RN 1062161-90-3
IUPAC Nombre:
methyl N-{4-[4-(morpholin-4-yl)-1-{1-[(pyridin-3-yl)methyl]piperidin-4-yl}-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl}carbamate
Sinónimos:
methyl N-{4-[4-(morpholin-4-yl)-1-[1-(pyridin-3-ylmethyl)piperidin-4-yl]pyrazolo[3,4-d]pyrimidin-6-yl]phenyl}carbamate
Peso molecular (g/mol):
528.62
Fórmula molecular:
C28H32N8O3
InChi Key:
VDOCQQKGPJENHJ-UHFFFAOYSA-N
SMILES:
COC(=O)NC1=CC=C(C=C1)C1=NC(N2CCOCC2)=C2C=NN(C3CCN(CC4=CN=CC=C4)CC3)C2=N1
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1
Tocris Bioscience™ WYE 687 dihydrochloride
CAS: 1062161-90-3 Fórmula molecular: C28H32N8O3
2
WYE-687, MedChemExpress
MedChemExpress WYE-687 is an ATP-competitive mTOR inhibitor with an IC50 of 7 nM. WYE-687 concurrently inhibits activation of mTORC1 and mTORC2. WYE-687 also inhibits PI3Kα and PI3Kγ with IC50s of 81 nM and 3.11 μM, respectively.
