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  5. Tocris Bioscience™ XIE62-1004

Tocris Bioscience™ XIE62-1004
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Produktkod. 18776025
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Cantidad:
10 mg
50 mg
Förpackningsstorlek:
10 miligramos
50 miligramos
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18776025 50 mg 50 miligramos
18766155 10 mg 10 miligramos
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Produktkod. 18776025 Leverantör Tocris Bioscience™ Leverantörsnummer 7878/50

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Beskrivning

Inducer of autophagy via interaction of p62 and LC3

XIE62-1004 is an inducer of p62-LC3 interaction. Binds to the ZZ domain of p62, leading to p62 self-aggregation and interaction with LC3 on autophagosome membranes; facilitates delivery of cargo proteins to the autophagosome for degradation. Active in vitro and in vivo in a concentration- and time-dependent manner and is specific for wild type p62. Induces degradation of mutant huntingtin in vitro. Can also be used in AUTAC protein degradation systems to induce autophagy through p62 self-aggregation and LC3 interaction.
TRUSTED_SUSTAINABILITY

Specifikationer

Nombre del producto químico o material 2-[[[3,4-Bis(phenylmethoxy)phenyl]methyl]amino]ethanol hydrochloride
CAS 2421146-32-7
Cantidad 50 mg
Objetivo p62/SQSTM1
Fórmula molecular C23H25NO3.HCl
Pureza 0.98
Produkttitel
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