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Invitrogen™ VPS34 Polyclonal Antibody
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Código de producto. 10018943
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Código de producto. Cantidad unitSize
10018943 100 μL 100 microlitros
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Código de producto. 10018943

Marca: Invitrogen™ PA146456

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Description

Rabbit Polyclonal Antibody

The target sequence has 87% sequence homology with xenopus. Suggested positive control: HepG2 whole cell lysates, antigen standard for PIK3C3 (transient overexpression lysate).

PIK3C3 (hVPS34) is the sole class III member of the PI3 Kinase family. PIK3C3 phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 3-phosphate [PI(3)P], which recruits downstream effectors containing FYVE and Phox domains to membranes. PIK3C3 is involved in coupling nutrient signaling to mTOR and also plays a role in autophagy and intracellular trafficking. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno VPS34
Aplicaciones Western Blot, Immunocytochemistry
Clasificación Polyclonal
Concentración 0.2 mg/mL
Conjugado Unconjugated
Formulación PBS with 0.1% BSA, 50% glycerol and 0.05% sodium azide
génica Pik3c3
N.º de referencia del gen O88763, Q5D891, Q6PF93, Q8NEB9
Alias de gen 5330434F23Rik; catalytic phosphatidylinositol 3-kinase 3; catalytic subunit type 3 Antibody; class 3 phosphoinositide-3-kinase; Class III PI 3-kinase; hVps34; hVps34 Antibody; OTTMUSP00000023341; OTTMUSP00000023350; phosphatidylinositol 3-kinase; Phosphatidylinositol 3-kinase catalytic subunit type 3; phosphatidylinositol 3-kinase p100 subunit; phosphatidylinositol 3-kinase, catalytic subunit type 3; Phosphoinositide-3-kinase class 3; phosphoinositide-3-kinase, class 3; PI3K type 3; PI-3K Vps34p; pi3kc3; PI3-kinase type 3; Pik3c3; PIK3C3 Antibody; PtdIns-3-kinase type 3; VPS34
Símbolos de los genes Pik3c3
Especie del huésped Rabbit
Inmunógeno Synthetic peptide made to an internal portion of the human VPS34 protein (within residues 700-850).
Método de purificación Antigen affinity chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 225326, 503700, 5289, 65052
Especies diana Human, Mouse, Rat, Pig
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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