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Thermo Scientific Chemicals Inhibidor II de la UPA, UK122
Marca: Thermo Scientific Chemicals J64874.MB
Detalles adicionales : CAS : 1186653-73-5 Peso : 0.00025kg
Descripción
A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activatoruPA Inhibitor II, UK122 acts as a potent, selective and active-site targeting urokinase-type plasminogen activator (uPA) inhibitor. However, its activity against trypsin, thrombin, tPA, and plasmin is greatly reduced. It is also effectively inhibits the migration (80% inhibition) and invasion (68% inhibition) of uPA-expressing CFPAC-1 pancreatic cells, without affecting its proliferation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
- Un compuesto de oxazolidinona-carboxamidina que puede penetrar en las células que actúa como un inhibidor potente, selectivo y activo del activador del plasminógeno de tipo urocinasa.
Especificaciones
25 mg | |
De 2 °C a 8 °C | |
C17H13N3O2·CF3CO2H | |
Sensible a la luz | |
Sólido |
Amarillo | |
Un compuesto de oxazolidinona-carboxamidina que puede penetrar en las células que actúa como un inhibidor potente, selectivo y activo del activador del plasminógeno de tipo urocinasa. | |
405,30g/mol | |
Reactivo de transducción de señales |
RUO – Research Use Only