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  6. Thermo Scientific Chemicals U-73122, 95 %

Thermo Scientific Chemicals U-73122, 95 %

Código de producto. 15475189
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5 mg
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Tamaño de la unidad:
1 miligramo
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Código de producto. Cantidad Tamaño de la unidad
15475189 10 mg 10 miligramos
15455189 5 mg 5 miligramos
15465189 1 mg 1 miligramo
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Código de producto. 15475189 Proveedor Thermo Scientific Chemicals N.º de proveedor J62898.MA
 Artículo restringido
Fecha estimada de envoi: 29-09-2026
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Description

It is used as a phospholipase C, phospholipase A2, and 5-LO inhibitor. It is also determined that in SK-N-SH neuroblastoma cells, U-73122 inhibits agonist-induced down-regulation of muscarinic receptors. In addition, it is a useful tool to investigate receptor-mediated PI turnover in signal transduction. U-73122 is a potent inhibitor of human neutrophil adhesion to biological surfaces (IC50 = 50 nM) as well as adhesion-dependent granule exocytosis and oxidative burst. U-73343 (sc-201422) is useful as a negative control for investigations of U-73122 phospholipase C antagonism and its cellular consequences.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Inhibidor de la activación de la fosfolipasa C y de la regulación descendente de los receptores muscarínicos.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 112648-68-7
Fórmula molecular C29H40N2O3
Sinónimo 1-[6-[(17beta)-3-metoxiestra-1,3,5[10]-trien-17-il)amino]hexil]pirrolo-2,5-diona

Specifications

Cantidad 10 mg
Descripción Blanco apagado
Para utilizar con (aplicación) Inhibidor de la activación de la fosfolipasa C y de la regulación descendente de los receptores muscarínicos
ensayo ≥99%
Formula Weight (peso de la fórmula) 464,65g/mol
Solubilidad Soluble en DMSO, etanol o DMF a 0,5 mg/ml aproximadamente; puede requerir calentamiento o mezclado durante la noche; no soluble en agua
Tipo de producto Reactivo de transducción de señales
Formulario Sólido cristalino

RUO – Research Use Only

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