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STEMCELL Technologies TTNPB

Código de producto. 17150142
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Cantidad:
10 mg
Tamaño de la unidad:
10 miligramos
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17150142 10 mg 10 miligramos
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Código de producto. 17150142 Proveedor STEMCELL Technologies N.º de proveedor 72892

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Description

Retinoid pathway activator; Activates retinoic acid receptor (RAR)

  • TTNPB is an analog of retinoic acid that potently and selectively activates retinoic acid receptors (RAR; EC50 = 21, 4, and 2.4 nM for RARα, RARβ, and RARγ, respectively; Beard et al.; Wong et al.)
  • In combination with CHIR99021 or Activin A, induces intermediate mesoderm formation from human or mouse pluripotent stem cells, respectively (Araoka et al.; Oeda et al.)
  • Promotes neuronal differentiation in cultured chick caudal neural plate explants (Diez del Corral et al.)
  • Enables chemical reprogramming (without genetic factors) of mouse embryonic fibroblasts to induced pluripotent stem (iPS) cells, in combination with CHIR99021, Tranylcypromine, VaLproic Acid, 3-Deazaneplanocin A, and E-616452 (Hou et al.)
  • Induces the in vitro growth and differentiation to granulocytes of myeloid progenitors isolated from myelodysplastic syndrome (MDS) patients (Fabian et al.)

Spécification

CAS 71441-28-6
Sinónimo AGN 191183; Arotinoid Acid; Ro 13-7410
Cantidad 10 mg
Fórmula molecular C24H28O2
Pureza ≥98%
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