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TP0463518, MedChemExpress
Description
TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1/PHD3 with IC50s of 18 and 63 nM as well as monkey PHD2 with an IC50 value of 22 nM.
Specifications
Specifications
| Nombre del producto químico o material | TP0463518 |
| CAS | 1558021-37-6 |
| Color | Light Yellow |
| Notas de grado de pureza | Research |
| Fórmula molecular | C20H18ClN3O6 |
| Cantidad | 10 mg |
| Información de solubilidad | DMSO : ≥ 125 mg/mL (289.47 mM) |
| SMILES | ClC(C=C1)=CC=C1OC2=NC=C(CN3C(C(C(NCC(O)=O)=O)=C(O)CC3)=O)C=C2 |
| Peso molecular (g/mol) | 431.83 |
| Formula Weight (peso de la fórmula) | 431.83 |
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Research purposes only
Product Title
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