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PeproTech Thrombopoietin Polyclonal Antibody, PeproTech®, Invitrogen™
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Código de producto. 17825283
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Cantidad:
1 mg
100 μg
50 μg
Tamaño de la unidad:
1 miligramo
100 microgramos
50 microgramos
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17825283 100 μg 100 microgramos
17815283 50 μg 50 microgramos
17864963 1 mg 1 miligramo
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Código de producto. 17825283 Proveedor PeproTech N.º de proveedor 500P49G100UG

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Descripción

Goat Polyclonal Antibody

AA Sequence of recombinant protein: SPAPPACDLR VLSKLLRDSH VLHSRLSQCP EVHPLPTPVL LPAVDFSLGE WKTQMEETKA QDILGAVTLL LEGVMAARGQ LGPTCLSSLL GQLSGQVRLL LGALQSLLGT QLPPQGRTTA HKDPNAIFLS FQHLLRGKVR FLMLVGGSTL CVRRAPPTTA VPSRTSLVLT LNEL. Preparation: Produced from sera of goats immunized with highly pure Recombinant Human TPO. Anti-Human TPO-specific antibody was purified by affinity chromatography employing an immobilized Human TPO matrix. Sandwich ELISA: To detect Human TPO by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human TPO (500-P49GBt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human TPO. Western Blot: To detect Human TPO by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human TPO is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, ultimately, to the production of platelets (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno Thrombopoietin
Aplicaciones ELISA, Western Blot
Clasificación Polyclonal
Concentración 0.1-1.0 mg/mL
Conjugado Unconjugated
Formulación PBS with no preservative
génica THPO
N.º de referencia del gen P40225
Alias de gen C-mpl ligand; Megakaryocyte colony-stimulating factor; megakaryocyte growth and development factor; megakaryocyte stimulating factor; Mgdf; MKCSF; ML; MPL ligand; Mpllg; MSA; Myeloproliferative leukemia virus oncogene ligand; prepro-thrombopoietin; TDH2A; THCYT1; THPO; Thrombopoietin; thyroid microsomal antigen; thyroid peroxidase; thyroperoxidase; Tpo; TPX
Símbolos de los genes THPO
Especie del huésped Goat
Inmunógeno E.coli-derived Recombinant Human TPO.
Método de purificación Antigen affinity chromatography
Cantidad 100 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 7066
Especies diana Human
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Lyophilized
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