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Invitrogen™ SMO Monoclonal Antibody (1015418)
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Product Code. 30535838
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Cantidad:
100 μg
Unit Size:
100 microgramos
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Product Code. Cantidad unitSize
30535838 100 μg 100 microgramos
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Product Code. 30535838 Supplier Invitrogen™ Supplier No. MA560873

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Description

Mouse Monoclonal Antibody

Reconstitute at 0.5 mg/mL in sterile PBS.

Smoothened drosophila homolog (SMOH) is a serpentine protein belonging to the G-protein coupled receptor Fz/Smo family with 787 aa, seven transmembrane G protein-coupled receptors with 4 glycosylation sites and a putative extracellular amino terminus. Smoothened activated by b-Arrestin 2 and GRK2 acts as a receptor for Shh, the Sonic hedgehog gene product, and is a positive regulator of hedgehog signaling pathway along with the smoothened inhibitor patched protein (PTCH) and regulates vertebrate developmental processes, cellular proliferation and differentiation by activating transcription factor Gli. Smoothened mutants are known to cause sporadic basal cell carcinoma of the skin. It is known to express widely in heart and brain.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno SMO
Aplicaciones Immunohistochemistry (Paraffin)
Clasificación Monoclonal
Clon 1015418
Concentración 0.5 mg/mL
Conjugado Unconjugated
Formulación PBS with 5% trehalose and no preservative
génica SMO
N.º de referencia del gen Q99835
Alias de gen bent body; bnb; E130215L21Rik; frizzled family member 11; FZD11; Gx; HGNC:11119; Protein Gx; Protein SMOH; seven transmembrane helix receptor; SMO; SMOH; smoothened; Smoothened homolog; smoothened homolog (Drosophila); smoothened, frizzled class receptor; smoothened, frizzled family receptor; smoothened, seven transmembrane spanning receptor
Símbolos de los genes SMO
Especie del huésped Mouse
Inmunógeno Chinese Hamster Ovary cell line, CHO-derived human Smoothened, Met1-Tyr233.
Método de purificación Protein A/G
Cantidad 100 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 6608
Especies diana Human
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Lyophilized
Isotype IgG2a
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