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Invitrogen™ SCNN1D Polyclonal Antibody
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Código de producto. 13485367
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
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13485367 100 μL 100 microlitros
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Código de producto. 13485367 Proveedor Invitrogen™ N.º de proveedor PA530864

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Descripción

Rabbit Polyclonal Antibody

Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7. Predicted reactivity: Chimpanzee (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor preferences. Conversely, SNX6 behaved similarly to the other SNX proteins in its interactions with receptor tyrosine kinases. Strong heteromeric interactions were also seen among SNX1, -2, -4, and -6, suggesting the formation in vivo of oligomeric complexes. These findings are the first evidence for the association of the SNX family of molecules with receptor serine-threonine kinases.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno SCNN1D
Aplicaciones Western Blot
Clasificación Polyclonal
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
génica SCNN1D
N.º de referencia del gen P51172
Alias de gen Amiloride-sensitive sodium channel subunit delta; delta-ENaC; Delta-NaCH; DNACH; ENaCd; ENaCdelta; epithelial Na(+) channel subunit delta; MGC149710; Nonvoltage-gated sodium channel 1 subunit delta; SCNED; SCNN1D; sodium channel epithelial 1 delta subunit; sodium channel, non voltage gated 1 delta subunit; sodium channel, nonvoltage-gated 1, delta; sodium channel, non-voltage-gated 1, delta subunit; sodium channel, voltage-gated, type I, delta polypeptide
Símbolos de los genes SCNN1D
Especie del huésped Rabbit
Inmunógeno Recombinant protein encompassing a sequence within the center region of human SCNN1D. The exact sequence is proprietary.
Método de purificación Antigen affinity chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 6339
Especies diana Human
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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