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  8. RN-1734, MedChemExpress

RN-1734, MedChemExpress

Código de producto. 16483917
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Artikelnummer. Cantidad unitSize
16483917 50 mg 50 miligramos
16450458 5 mg 5 miligramos
16427776 100 mg 100 miligramos
16417998 10 mg 10 miligramos
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Artikelnummer. 16483917 Leverandør Medchem Express Leverandørnr. HY19975

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Beskrivelse

MedChemExpress RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 μM, mTRPV4: 5.9 μM, rTRPV4: 3.2 μM). RN-1734 clearly decreases the production of tumor necrosis factor α (TNF-α) and interleukin 1β (IL-1β) without altering the number of olig2-positive cells.

RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 μM, mTRPV4: 5.9 μM, rTRPV4: 3.2 μM). RN-1734 clearly decreases the production of tumor necrosis factor α (TNF-α) and interleukin 1β (IL-1β) without altering the number of olig2-positive cells.

Tekniske data

Nombre del producto químico o material RN-1734
CAS 946387-07-1
Color Blanco
Notas de grado de pureza Research
Fórmula molecular C14H22Cl2N2O2S
Cantidad 50 mg
Información de solubilidad DMSO : 25 mg/mL (70.76 mM; ultrasonic and warming and heat to 60°C)
SMILES O=S(C1=CC=C(Cl)C=C1Cl)(N(C(C)C)CCNC(C)C)=O
Peso molecular (g/mol) 353.31
Formula Weight (peso de la fórmula) 353.31
Porcentaje de pureza 98.99%
Grado Research
Forma física Solid
Para utilizar con (aplicación) Neuroscience-Neuromodulation
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Research purposes only

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