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  5. Tocris Bioscience™ RIPA 56

Tocris Bioscience™ RIPA 56
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Product Code. 18708426
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Cantidad:
10 mg
50 mg
Unit Size:
10 miligramos
50 miligramos
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18708426 10 mg 10 miligramos
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Product Code. 18708426 Supplier Tocris Bioscience™ Supplier No. 7339/10

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Description

Potent and metabolically stable RIP1 kinase inhibitor

RIPA 56 is a potent and metabolically stable receptor-interacting protein kinase 1 (RIPK1) inhibitor (EC50 = 13 nM). RIPA-56 shows no inhibition of RIP3 kinase at 10 μM . RIPA 56 blocks necroptosis and aging of the mouse male reproductive system. RIPA 56 reduces tumor necrosis factor α (TNFα)-induced mortality and multi-organ damage in a mouse model of systemic inflammatory response syndrome (SIRS). RIPA 56 is orally bioavailable.
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Specifications

Nombre del producto químico o material N-Hydroxy-2,2-dimethyl-N-(phenylmethyl)butanamide
CAS 1956370-21-0
Cantidad 10 mg
Objetivo RIP Kinase Inhibitors
Fórmula molecular C13H19NO2
Pureza 0.98
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