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SMAD3 (phospho T179), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Código de producto. 16074267
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Cantidad:
100 μg
Tamaño de la unidad:
100 microgramos
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16074267 100 μg 100 microgramos
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Código de producto. 16074267 Proveedor Abnova N.º de proveedor PAB19947.100ug

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Descripción

Rabbit polyclonal antibody raised against synthetic phosphopeptide of SMAD3.

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq]

Especificaciones

Antígeno SMAD3
Aplicaciones ELISA, Immunohistochemistry, Western Blot
Clasificación Polyclonal
Conjugado Unconjugated
Descripción Rabbit polyclonal antibody raised against synthetic phosphopeptide of SMAD3.
Dilución ELISA (1:15000-1:75000) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Formulación In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide)
génica SMAD3
Alias de gen DKFZp586N0721/DKFZp686J10186/HSPC193/HsT17436/JV15-2/MADH3/MGC60396
Símbolos de los genes SMAD3
Especie del huésped Rabbit
Inmunógeno Synthetic phosphopeptide corresponding to residues surrounding T179 of human SMAD3.
Método de purificación Affinity purification
Cantidad 100 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 4088
Especificidad de la prueba This affinity-purified antibody is directed against the phosphorylated form of human Smad3 protein at the pT179 residue. The product was affinity purified from monospecific antiserum by immunoaffinity purification. Antiserum was first purified against the phosphorylated form of the immunizing peptide. The resultant affinity purified antibody was then cross adsorbed against the non-phosphorylated form of the immunizing peptide. Reactivity occurs against human Smad3 pT179 protein and the antibody is specific for the phosphorylated form of the protein. Reactivity with non-phosphorylated human Smad3 is minimal by ELISA and western blot. Expect reactivity against phosphorylated Smad2. Reactivity against other phosphorylated Smad family members is not known. A BLAST analysis was used to suggest cross reactivity with Smad3 from human, mouse, rat, pig, dog, and marmoset based on 100% sequence homology with the immunogen. Reactivity against homologues from other sources is not known.
Especies diana Human
Contenido y almacenamiento Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Formulario Liquid
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For Research Use Only

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