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Thermo Scientific™ (R,R)-Chloramphenicol, 98%
(R,R)-Chloramphenicol, CAS # 56-75-7, also known as chloromycetin, is a compound with broad-spectrum antibiotic and bacteriostatic activities.
Marca: Thermo Scientific™ B20841.14
| Cantidad | 25g |
|---|
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Descripción
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
- (R,R)-chloramphenicol is a compound with antibiotic and bacteriostatic activity and is derived from Streptomyces venequelae
- It that can block the translation on the 50S subunit at the peptidyltransferase step. The binding affects the peptidyl transferase activity, preventing the transfer of amino acids to the growing peptide chains and inhibiting peptide bond formation. The resulting inhibition of the bacterial protein synthesis impedes bacterial cell proliferation
Application
- (R,R)-chloramphenicol has been used for several molecular biology approaches, mainly for bacterial selection. It can be used to select transformed cells containing chloramphenicol resistance genes
- This compound can also promote mitochondrial and chloroplast protein synthesis and the ribosomal formation of (p)ppGpp, depressing the rRNA transcription process
- In vitro results demonstrate that (R,R)-chloramphenicol shows activity against several vancomycin-resistant E. faecium strains
Identificadores de productos químicos
| 56-75-7 | |
| 323.126 | |
| WIIZWVCIJKGZOK-RKDXNWHRSA-N | |
| CHEBI:17698 | |
| C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-] |
| C11H12Cl2N2O5 | |
| MFCD00078159 | |
| 5959 | |
| 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide |
Especificaciones
| Chloramphenicol | |
| 25g | |
| C11H12Cl2N2O5 | |
| 2225532 | |
| Soluble in alcohol,propylene,glycol,acetone and ethyl acetate. Slightly soluble in water. | |
| C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-] | |
| 323.126 | |
| CHEBI:17698 | |
| ≥99% |
| 56-75-7 | |
| 0.99 | |
| MFCD00078159 | |
| 14,2077 | |
| WIIZWVCIJKGZOK-RKDXNWHRSA-N | |
| 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide | |
| 5959 | |
| 323.14 |
Seguridad y manipulación
Nombre del producto
Palabra de advertencia
Clasificación
Indicaciones de peligro
Consejos de prudencia
Otros peligros
- (R,R)-Chloramphenicol
Palabra de advertencia
- Peligro
Clasificación
- Carcinogenicidad Categoría 1B
Indicaciones de peligro
- H350-Puede provocar cáncer.
Consejos de prudencia
- P201-Pedir instrucciones especiales antes del uso.
- P308+P313-EN CASO DE exposición manifiesta o presunta: Consultar a un médico.
Otros peligros
- MIXTURE LIST-Contain: Chloramphenicol
Título del producto
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