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(R)-(-)-Deprenyl hydrochloride, Thermo Scientific™

Selective MAO-B inhibitor; anti-Parkinsonian agent

Marca:  Thermo Scientific Alfa Aesar J61286.MD

Cantidad 250mg

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Código de producto. 15483899

  • 75.40€ / 250 miligramos

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Descripción

Descripción

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
(R)-(-)-Deprenyl hydrochloride provides neuroprotection which may be relevant to Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and stroke. It is an inhibitor of MAO-B (monoamine oxidase-B) which demonstrates extensive neuroprotective effects shown to be uncorrelated with MAO-B inhibiting activity. It demonstrates protection of dopaminergic neurons from excitotoxicity mediated by NMDA activation. It also demonstrates decreases in apoptosis of PC12 neuronal cells accompanied with an induction of new protein synthesis through direct transcriptional and translational interaction, and reduced cell death and internucleosomal DNA degredation at concentrations too low to inhibit MAO-B.

Solubility
Soluble in water at 100mM

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
TRUSTED_SUSTAINABILITY
Especificaciones

Identificadores de productos químicos

14611-52-0
223.74
IYETZZCWLLUHIJ-UTONKHPSSA-N
26758
hydrogen methyl[(2R)-1-phenylpropan-2-yl](prop-2-yn-1-yl)amine chloride
C13H18ClN
MFCD00069299
selegiline hydrochloride, eldepryl, zelapar, selegiline hcl, l-deprenyl hydrochloride, jumex hydrochloride, --deprenyl hydrochloride, eldepryl hydrochloride, r-n-methyl-n-1-phenylpropan-2-yl prop-2-yn-1-amine hydrochloride, zydis selegiline
CHEBI:9087
[H+].[Cl-].C[C@H](CC1=CC=CC=C1)N(C)CC#C

Especificaciones

(R)-(-)-Deprenyl hydrochloride
C13H18ClN
250mg
selegiline hydrochloride, eldepryl, zelapar, selegiline hcl, l-deprenyl hydrochloride, jumex hydrochloride, --deprenyl hydrochloride, eldepryl hydrochloride, r-n-methyl-n-1-phenylpropan-2-yl prop-2-yn-1-amine hydrochloride, zydis selegiline
IYETZZCWLLUHIJ-UTONKHPSSA-N
[H+].[Cl-].C[C@H](CC1=CC=CC=C1)N(C)CC#C
223.74
CHEBI:9087
14611-52-0
MFCD00069299
14,8428
Soluble in water at 100mM
−12° (c=1 in Water)
hydrogen methyl[(2R)-1-phenylpropan-2-yl](prop-2-yn-1-yl)amine chloride
26758
223.74
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