R&D Systems™ Quantikine Immunoassay Control Set 918 for Human IGF-II/IGF2

Insulin-like growth factor (IGF)-I (also known as somatomedin C and somatomedin A), IGF-II (multiplication stimulating activity or MSA) belongs to family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGF-I and IGF-II share approximately 70% sequence identity. Both IGF-I and IGF-II are expressed in many tissues, cell types, may have autocrine, paracrine, endocrine functions. Mature IGF-I and IGF-II are highly conserved between human, bovine, porcine proteins (100% identity), exhibits cross-species activity. The IGFL (insulin-like growth factor-like) family includes four small (∼11 kDa), probably secreted family members in humans, one in mouse. This family shares A and B chain cysteine motifs with IGF superfamily, and has additional cysteine motif within uncleaved region corresponding to C peptide of IGF family.

• Storage: Store unopened product at 2 to 8°C. Do not use past expiration date.