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Invitrogen™ Phospho-PRAS40 (Thr246) Polyclonal Antibody
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Código de producto. 16580232
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
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16580232 100 μL 100 microlitros
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Código de producto. 16580232 Proveedor Invitrogen™ N.º de proveedor PA597402

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Descrizione

Rabbit Polyclonal Antibody

Immunogen sequence: LNTSD; Positive Samples: HeLa; Cellular Location: Cytoplasm, cytosol.

The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia. AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can induce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells.
TRUSTED_SUSTAINABILITY

Specifica

Antígeno Phospho-PRAS40 (Thr246)
Aplicaciones ELISA, Western Blot, Immunocytochemistry
Clasificación Polyclonal
Concentración 0.99 mg/mL
Conjugado Unconjugated
Formulación PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
génica AKT1S1
N.º de referencia del gen Q96B36
Alias de gen 1110012J22Rik; 40 kDa proline-rich AKT substrate; AI227026; AKT1 substrate 1; AKT1 substrate 1 (proline rich); AKT1 substrate 1 (proline-rich); akt1s1; Lobe; Lobel; OTTHUMP00000196756; OTTHUMP00000196760; PKB/Akt substrate 40; Pras; PRAS40; Proline-rich AKT substrate; proline-rich AKT1 substrate 1
Símbolos de los genes AKT1S1
Especie del huésped Rabbit
Inmunógeno Synthetic peptide
Método de purificación Affinity Chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 84335
Especies diana Human
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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