missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Tocris Bioscience™ PFK 15
Selective PFKFB3 inhibitor
Marca: Tocris Bioscience™ 5339/10
Este artículo no se puede devolver.
Vea la política de devoluciones
Descripción
PFK 15 is an originally reported to be a selective PFKFB3 inhibitor (IC50 = 207 nM); a more recent report failed to demonstrate activity in a PFKFB3 kinase assay. Selective for PFKFB3 over a panel of 96 kinases. Reduces glucose uptake and induces apoptosis in H522 lung adenocarcinoma and Jurkat T cell leukemia cells. Suppresses glucose uptake and tumor growth, and inhibits metastasis of Lewis lung carcinoma cell xenografts in mice.Especificaciones
| PFK 15 | |
| 1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one | |
| Soluble to 100mM in DMSO | |
| Bioactive Small Molecule |
| 4382-63-2 | |
| 10 mg | |
| Solid |
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?
Research Use Only. Not For Human or Veterinary Use