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NXT629, MedChemExpress

Código de producto. 16477547
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Código de producto. Cantidad unitSize
16477547 5 mg 5 miligramos
16471067 50 mg 50 miligramos
16415606 100 mg 100 miligramos
16414808 10 mg 10 miligramos
16403256 25 mg 25 miligramos
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Código de producto. 16477547 Proveedor Medchem Express N.º de proveedor HY114263

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Descripción

MedChemExpress NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively. NXT629 has potent anti-tumor activity and inhibits experimental metastasis of cancer cell in animal models.

NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively. NXT629 has potent anti-tumor activity and inhibits experimental metastasis of cancer cell in animal models.

Especificaciones

Nombre del producto químico o material NXT629
CAS 1454925-59-7
Color Light Yellow
Notas de grado de pureza Research
Fórmula molecular C35H39N5O3S
Cantidad 5 mg
Información de solubilidad DMSO : 125 mg/mL (204.99 mM; Need ultrasonic)
SMILES O=S(C1=CC=CC=C1)(NC2=CC=C(C3=CC=C(CCCC(N4CC)=NN(CC5=CC=C(C(C)(C)C)C=C5)C4=O)C=C3)N=C2)=O
Peso molecular (g/mol) 609.78
Formula Weight (peso de la fórmula) 609.78
Porcentaje de pureza 99.2%
Grado Research
Forma física Solid
Para utilizar con (aplicación) Cancer-programmed cell death
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Research purposes only

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