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Descripción
Immunogen sequence: SREPYKDIGK MSLPSGHTTG HTDQVVQRRA RCWDIYQRRF SSRSEPVNPG MHSSSHQQQD GDAAMHGAHM DSPVRYTPYT ISPYNRKGSF RKQDQTHVNM EREQKPPERR MEGNMPDGTL GSWFKITVPF GIKYNEKWLL NL Highest antigen sequence identity to the following orthologs: Mouse - 38%, Rat - 39%.
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.
Especificaciones
Especificaciones
| Antígeno | NXF3 |
| Aplicaciones | Immunohistochemistry (Paraffin), Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 0.05 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| génica | NXF3 |
| N.º de referencia del gen | Q9H4D5 |
| Alias de gen | Nuclear RNA export factor 3; NXF3; RGD1564923; TAPL3; TAPL-3; TAP-like protein 3 |
| Símbolos de los genes | NXF3 |
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Título del producto
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