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NKL 22, MedChemExpress

Código de producto. 16499546
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Product Code. 16499546 Supplier Medchem Express Supplier No. HY100384

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Description

MedChemExpress NKL 22 (compound 4b) is a potent and selective inhibitor of histone deacetylases (HDAC), with an IC50 of 199 and 69 nM for HDAC1 and HDAC3, respectively. NKL 22 exhibits selectivity over HDAC2/4/5/7/8 (IC50≥1.59 μM). NKL 22 ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice.

NKL 22 (compound 4b) is a potent and selective inhibitor of histone deacetylases (HDAC), with an IC50 of 199 and 69 nM for HDAC1 and HDAC3, respectively. NKL 22 exhibits selectivity over HDAC2/4/5/7/8 (IC50≥1.59 μM). NKL 22 ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice.

Specifications

Nombre del producto químico o material NKL 22
Forma física Solid
CAS 537034-15-4
Color Blanco
Cantidad 50 mg
Notas de grado de pureza Research
Fórmula molecular C19H23N3O2
Para utilizar con (aplicación) Cancer-programmed cell death
Información de solubilidad DMSO : ≥ 29 mg/mL (89.12 mM)
SMILES O=C(NC1=CC=CC=C1N)CCCCCC(NC2=CC=CC=C2)=O
Peso molecular (g/mol) 325.4
Formula Weight (peso de la fórmula) 325.4
Porcentaje de pureza 97.27%
Grado Research
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Research purposes only

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