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N-Acetil-D-manosamina, 98 %, Thermo Scientific Chemicals
Tienda Thermo Scientific Chemicals ProductosBeschreibung
Este producto de marca Thermo Scientific formó parte originalmente de la cartera de productos Acros Organics.Alguna información sobre documentos y etiquetas puede referirse a la marca original.El producto original de Acros Organics / código de artículo o referencia SKU no ha cambiado como parte de la transición de marca a Thermo Scientific.
General Description
- N-Acetyl-D-mannosamine (ManNAc) is a precursor used to synthesize N-acetylneuraminic acid, the most common physiologic sialic acid present in humans and other mammals
- Sialic acids are terminal sugars on glycoconjugates that can modify biochemistry of glycoproteins and lipids, mediate cellular adhesion, and act as immune regulators
- Defects in sialic acid biosynthesis are associated with a number of pathologies
- Sialic acids are often found at increased expression levels on tumor cell surfaces
Applications
- As a sialic acid precursor, N-Acetyl-D-mannosamine can be used in many glycoengineering applications, such as modifying immune cell activity, imaging glycans, or blocking pathogen binding
- N-Acetyl-D-mannosamine hasbeen used in preclinical laboratory studies as a treatment for hereditary inclusion body myopathy, a progressive neuromuscular disease via increased sialylation of podocalyxin
- N-Acetyl-D-mannosamine has been used in laboratory studies to induce IgG sialylation and prevent obesity-induced hypertension in mice following high-fat diet
Spezifikation
Spezifikation
| Nombre del producto químico o material | N-Acetyl-D-mannosamine |
| % mín. CAS | 97.5 |
| % máx. CAS | 100.0 |
| Color | Blanco |
| Espectro infrarrojo | Authentic |
| Intervalo de porcentaje de ensayo | 98% |
| Envase | Frasco de vidrio |
| Cantidad | 5 g |
| Formula Weight (peso de la fórmula) | 221.21 |
| Porcentaje de pureza | ≥97.5% |
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RUO – Research Use Only
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