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ML364, MedChemExpress

Product Code. 16454486
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Product Code. Cantidad unitSize
16454486 100 mg 100 miligramos
16445947 5 mg 5 miligramos
16423218 10 mg 10 miligramos
16419766 50 mg 50 miligramos
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Product Code. 16454486 Supplier Medchem Express Supplier No. HY100900

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Description

MedChemExpress ML364 is a selective ubiquitin specific peptidase 2 (USP2) inhibitor (IC50=1.1 μM) with anti-proliferative activity, which direct binds to USP2 (Kd=5.2 μM), induces an increase in cellular cyclin D1 degradation and causes cell cycle arrest. ML364 increases the levels of mitochondrial ROS and decreases in the intracellular content of ATP.

ML364 is a selective ubiquitin specific peptidase 2 (USP2) inhibitor (IC50=1.1 μM) with anti-proliferative activity, which direct binds to USP2 (Kd=5.2 μM), induces an increase in cellular cyclin D1 degradation and causes cell cycle arrest. ML364 increases the levels of mitochondrial ROS and decreases in the intracellular content of ATP.

Specifications

Nombre del producto químico o material ML364
CAS 1991986-30-1
Color off White
Notas de grado de pureza Research
Fórmula molecular C24H18F3N3O3S2
Cantidad 100 mg
Información de solubilidad DMSO : ≥ 33 mg/mL (63.76 mM)
SMILES O=C(NC1=NC(C2=CC=CC=C2)=CS1)C3=CC=C(C(F)(F)F)C=C3NS(=O)(C4=CC=C(C)C=C4)=O
Peso molecular (g/mol) 517.54
Formula Weight (peso de la fórmula) 517.54
Porcentaje de pureza 99.94%
Grado Research
Forma física Solid
Para utilizar con (aplicación) Cancer-programmed cell death
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Research purposes only

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