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Invitrogen™ Mitochondria Membrane Integrity Antibody Cocktail
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Código de producto. 10124863
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Cantidad:
255 μg
Tamaño de la unidad:
cada uno
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10124863 255 μg cada uno
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Código de producto. 10124863 Proveedor Invitrogen™ N.º de proveedor 457799

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Descripción

Antibody Cocktail

Mitochondria Membrane Integrity cocktail of monoclonal antibodies specific to human, bovine, mouse, rat mitochondria membranes. This antibody is validated for use in Western Blot, and can be used to assess mitochondrial membrane integrity during and after purification. Contains: 50 μg of Porin clone #2B12AF12 - Human VDAC1. Concentration 2 μg/mL. 50 μg of Cyclophilin D clone #E11AE12BD4 - Rat CypD/PPIF. Concentration 2 μg/mL. 50 μg of C-III-Core 1 clone # 16D10AD9AH5 - Bovine Heart Complex II/III. Concentration 2 μg/mL. 5 μg of Cytochrome C clone #37BA11 - Human Cytochrome c. Concentration 0.1 μg/mL. 100 μg of C-V-a clone #7H10BD4F9 - Bovine Complex V. Concentration 4 μg/mL. This antibody cocktail (2.37 mg/mL) should be diluted to a final working concentration of 10.2 μg/mL for use in Western blot applications.

Voltage-dependent anion channel (VDAC) proteins are abundant, pore-forming proteins belonging to the eukaryotic mitochondrial porins. It was discovered in the mitochondrial outer membrane. It also is expressed in the plasma membrane. At least three different VDAC genes have been identified in vertebrates. VDAC proteins are known to play an essential role in cellular metabolism and in the early stages of apoptosis. For example, VDAC contitutes a major pathway by which metabolites such as ADP/ATP, succinate and citrate are exchanged between the cytosol and mitochondria. And VDAC1 in the plasma membrane establishes a novel level of apoptosis regulation putatively via its redox activity.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno Mitochondria Membrane Integrity
Aplicaciones Western Blot
Clasificación Cocktail
Clon Cocktail
Concentración 2.37 mg/mL
Conjugado Unconjugated
Formulación HEPES buffered saline with 0.02% sodium azide
génica CYC1
N.º de referencia del gen P00125, P08574, P21796, P29117, P30404, P30405, P45879, P62894, P62897, P62898, P99999, Q60932, Q99KR7, Q9D0M3, Q9Z2L0
Alias de gen 16D10AD9AH5; 20B12AF2; 2610002H19Rik; 37BA11; 7H10BD4F9; AA408921; AL033343; AW457192; BR1-VDAC; brain-derived voltage-dependent anion channel 1; Complex III subunit 4; complex III subunit IV; CYC; Cyc1; cyclophilin 3; cyclophilin D; Cyclophilin F; Cycs; CYCSA; CYP3; CypD; CyP-D; CyP-F; CyP-M; cytc; Cytochrome b-c1 complex subunit 4; cytochrome c; Cytochrome C, expressed in somatic tissues; cytochrome c, somatic; cytochrome c1; Cytochrome c-1; cytochrome c1, heme protein, mitochondrial; E11AE12BD4; HCS; MC3DN6; MGC128356 protein; mitochondrial cyclophilin; mitochondrial Cyclophilin D; mVDAC1; mVDAC5; outer mitochondrial membrane protein porin 1; Peptidyl-prolyl cis-trans isomerase F, mitochondrial; peptidyl-prolyl cis-trans isomerase, mitochondrial; peptidylprolyl isomerase F; peptidylprolyl isomerase F (cyclophilin F); plasmalemmal porin; PORIN; Porin 31HL; porin 31HM; PPIase; PPIase F; PPIF; Rotamase F; rVDAC1; THC4; ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit; Unknown (protein for MGC:134266); UQCR4; VDAC; Vdac1; VDAC-1; Vdac5; VDAC-5; voltage dependent anion channel 1; voltage-dependent anion channel 1; voltage-dependent anion-selective channel protein 1; Voltage-dependent anion-selective channel protein 5
Símbolos de los genes CYC1, Cycs, PPIF, Vdac1
Especie del huésped Mouse
Método de purificación IgG fraction
Cantidad 255 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 10105, 105675, 13063, 1537, 22333, 25309, 282119, 282819, 300047, 414346, 510767, 512500, 54205, 66445, 7416, 83529
Especies diana Human, Mouse, Rat, Bovine
Contenido y almacenamiento 4°C
Tipo de producto Antibody
Formulario Liquid
Isotype Ig
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